Big Mac Casserole

Big Mac Casserole

Healthy Fact of the Day

Ground beef provides essential protein and B vitamins for energy and muscle health. Using lean ground beef and adding extra vegetables can boost the nutritional value while maintaining that classic flavor.

This Big Mac Casserole captures all the beloved flavors of the iconic fast-food burger in a family-friendly casserole format that’s perfect for weeknight dinners. Seasoned ground beef mingles with tangy pickle relish and creamy Thousand Island dressing, while melted cheddar cheese creates that signature burger taste. Built on a foundation of cubed bread that soaks up all the delicious flavors, it’s comfort food that brings back childhood memories with every bite.

If you love creative takes on classic favorites like this, you’ll also enjoy our Cheesesteak Tortellini in Provolone Sauce with its similar comfort food appeal and cheese-forward flavors. For another crowd-pleasing casserole, try the Tamale Casserole, which transforms another beloved dish into an easy-to-serve family meal.

Big Mac Casserole

Big Mac Casserole

Recipe by Daily Disher

Big Mac Casserole brings together seasoned ground beef, melted cheddar cheese, pickle relish, and Thousand Island dressing over a bread base for burger bliss.

Course: MainCuisine: AmericanDifficulty: Easy
4.0 from 13 votes
Servings

6

servings
Prep time

15

minutes
Cooking time

40

minutes
Calories

500

kcal

55

minutes

    Ingredients

    • 1 pound ground beef

    • 1 cup diced onions

    • 2 cups shredded cheddar cheese

    • 2 tablespoons pickle relish

    • 1 cup thousand island dressing

    • 4 cups cubed bread

    • 1 teaspoon salt

    • 0.5 teaspoon black pepper

    Directions

    • Preheat your oven to 350°F (175°C) and grease a 9×13-inch baking dish to prepare for baking.
    • In a large skillet over medium heat, cook the ground beef and diced onions until the beef is browned, about 8-10 minutes.
    • Drain any excess fat from the skillet and season the beef mixture with salt and black pepper.
    • Spread the cubed bread evenly in the prepared baking dish to form the base layer of the casserole.
    • Evenly distribute the cooked beef mixture over the layer of bread in the baking dish.
    • Sprinkle the shredded cheddar cheese evenly over the beef to ensure consistent melting and flavor throughout.
    • Drizzle the pickle relish and thousand island dressing evenly over the cheese layer for added taste.
    • Bake in the preheated oven for 25-30 minutes until the cheese is bubbly and the top is golden brown.
    • Allow the casserole to cool slightly before serving to ensure it holds its shape when sliced.

    Nutrition Facts

    • Total number of serves: 4
    • Calories: 250kcal
    • Cholesterol: 0mg
    • Sodium: 620mg
    • Potassium: 400mg
    • Sugar: 8g
    • Protein: 6g
    • Calcium: 60mg
    • Iron: 2mg

    Can’t get enough of great flavors? Check out these popular recipes that readers love making again and again.

    For hearty family favorites, our Hamburger Steak in Creamy Dill Sauce and Ground Turkey Sweet Potato Skillet deliver that perfect combination of satisfying protein and rich flavors. When you’re looking for more comfort food casseroles, the Green Chile Chicken and Rice Casserole and Smothered Pork Chop and Scalloped Potato Casserole bring warmth and convenience to your dinner table. Need quick weeknight solutions? Our Garlic Chicken with Broccoli and Spinach and Pineapple Chicken and Rice get dinner done fast without sacrificing flavor.

    Browse our full collection for more kitchen inspiration that’ll have your family asking for seconds.

    4.0 from 13 votes

    Recent Recipes

    Little Caesars’ Fan-Favorite Personal Pizza Deal Is

    • September 8, 2026
    • 2 min read

    Cantonese BBQ Brisket Is Back at Panda

    • September 6, 2026
    • 2 min read

    Wendy’s Halloween Kids’ Meal Is Back —

    • September 5, 2026
    • 2 min read

    Popeyes’ $6 Big Box Deal Is Back

    • September 4, 2026
    • 2 min read

    Aldi’s September 2026 Finds Are Stacked With

    • September 3, 2026
    • 3 min read

    Taco Bell Is Offering a $2 Combo

    • September 2, 2026
    • 2 min read

    Never-Ending Pasta Bowl Is Back at Olive

    • September 1, 2026
    • 2 min read

    Spicy Chicken McNuggets Are Officially Back at

    • August 31, 2026
    • 2 min read

    Stuffed Italian Meatloaf

    • August 27, 2026
    • 6 min read

    Why You’re Supposed to Let Meat Rest

    • August 27, 2026
    • 4 min read

    Tip of the Day

    “Always let your meat rest before slicing.”

    Whether you're roasting a chicken, grilling steak, or baking pork tenderloin, letting cooked meat rest for 5–10 minutes before slicing allows the juices to redistribute evenly. This simple step keeps your meat juicy and tender, ensuring every bite is flavorful and moist. Bonus: It gives you a moment to plate your sides or garnish for a perfect presentation!

    Our Latest Recipes

    Blog
    Daily Disher

    Little Caesars’ Fan-Favorite Personal Pizza Deal Is Back

    A pizza-and-bread combo can pack in a fair amount of refined carbs and sodium in one sitting, especially with dipping sauce added on top. To round things out, consider pairing the combo with a side salad or a piece of fruit to add some fiber, and going easy on the dipping sauce rather than using the full portion with every bite.

    Read More »
    Blog
    Daily Disher

    Cantonese BBQ Brisket Is Back at Panda Express After Selling Out Earlier This Summer

    Pairing a high-protein entrée with the right sides can help round out a more balanced meal. Consider choosing a vegetable-based side like mixed veggies instead of fried rice or chow mein to add fiber without extra refined carbs, and opting for a bowl over a plate if you’re looking to manage overall portion size while still getting the full protein benefit of the entrée.

    Read More »
    Blog
    Daily Disher

    Wendy’s Halloween Kids’ Meal Is Back — And Adults Are Ordering It Too

    Kids’ meals are portioned smaller than adult entrées, which can actually make them a reasonable option for a lighter meal or a snack-sized treat. To keep things balanced, consider pairing the meal with a side of apple bites instead of fries, choosing a lower-sugar beverage like milk or water over a fountain drink, and treating the Frosty as a dessert to enjoy on its own rather than adding it on top of a larger meal.

    Read More »

    Get your daily dose of delicious!

    Skip to content