This Mac and Cheese Meatloaf Casserole takes two beloved comfort foods and creates one irresistible dish. The seasoned ground beef forms a savory base topped with creamy, cheesy macaroni that bakes to golden perfection. It’s the ultimate family-friendly meal that satisfies everyone at the dinner table with minimal prep and maximum flavor.
If you love hearty casseroles like this, you’ll also enjoy our Tater Tot Casserole with its similar comfort food appeal and easy preparation. For another cheesy, satisfying meal, try the Everything Bagel Breakfast Casserole—it brings that same cozy, all-in-one convenience to your morning routine.
Mac and Cheese Meatloaf Casserole
This Tender Pineapple Pork transforms tough pork shoulder into succulent, shredded perfection with sweet pineapple juice, soy sauce, and warm spices in your slow cooker.
8
servings20
minutes1
hour500
kcalIngredients
2 cups macaroni
1 pound ground beef
1 cup breadcrumbs
1 cup diced onions
2 cloves garlic, minced
1 cup shredded cheddar cheese
1 cup milk
1 tablespoon ketchup
1 teaspoon salt
0.5 teaspoon black pepper
Directions
- Preheat the oven to 350°F (175°C) and grease a large baking dish.
- Cook macaroni according to package instructions in boiling water until slightly firm.
- In a bowl, combine ground beef, breadcrumbs, onions, garlic, salt, and black pepper.
- Press the meatloaf mixture into the prepared baking dish to form an even layer.
- Spread ketchup evenly over the top of the meat mixture.
- Bake in the preheated oven for 25 to 30 minutes until the meat is browned.
- Drain the cooked macaroni and mix with milk and half of the shredded cheese.
- Spread the macaroni mixture over the baked meatloaf and sprinkle remaining cheese on top.
- Return the dish to the oven and bake for an additional 20 minutes until cheese is melted.
- Let the casserole cool for a few minutes before serving to allow it to firm up slightly.
Nutrition Facts
- Total number of serves: 4
- Calories: 250kcal
- Cholesterol: 0mg
- Sodium: 620mg
- Potassium: 400mg
- Sugar: 8g
- Protein: 6g
- Calcium: 60mg
- Iron: 2mg
Can’t get enough of great flavors? Check out these popular recipes that readers love making again and again.
For more comforting casserole favorites, our Blueberry Buttermilk Pancake Casserole and Southern Breakfast Enchiladas with Sausage Gravy bring that same satisfying, family-style appeal. When you’re planning hearty dinners, the Oven Roasted Brisket and Smothered Pork Chop and Scalloped Potato Casserole deliver that stick-to-your-ribs comfort. Need quick weeknight solutions? Our Tamale Casserole and Green Chile Chicken and Rice Casserole get dinner on the table with minimal fuss.
Browse our full collection for more kitchen inspiration that’ll have your family asking for seconds.
